Low carb .. higher blood glucose numbers

A light bike doesn't replace good fitness.

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WinterRider
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by WinterRider

http://ketopia.com/high-blood-sugar-in- ... etabolism/

"I’m quite sure there will be many more future studies showing other genotypes that affect fat and carbohydrate metabolism, but we can now all agree there is no one best diet for everyone" Writes this author.

Gist of article is low carb diets in some induce what appears to be diabetic like tendencies ... yet in reality it is the body's response to low insulin levels.. IE: compensating with slightly higher glucose numbers.

This guy's list unfortunately of favorites on the right side includes 'diet mongers' .. those of precious little knowledge and full of agenda.

by Weenie


TheKaiser
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by TheKaiser

Yes, that is a counterintuitive effect of going low carb for many people. If you google "physiological insulin resistance" you'll find a lot of info on the topic. It seems that, basically, the body wants to conserve glucose, in order to ensure there is an adequate supply for the brain (even with an ample supply of ketones, the brain still needs some glucose as well). In order to keep an adequate level of glucose in the bloodstream to fuel the brain, there is a mechanism which induces insulin resistance in other tissues, in order to prevent them from sucking up that small and precious supply of glucose that the brain needs. There can be other things that drive high fasting blood sugar while on a low carb diet, like upregulated gluconeogenesis which increases the supply of glucose your body is synthesizing, but the physiological insulin resistance is what keeps it in the blood stream for extended periods, and what can compromise blood sugar regulation when you ingest carbs after a period of carb restricted dieting.

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WinterRider
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by WinterRider

TheKaiser wrote: upregulated gluconeogenesis which increases the supply of glucose your body is synthesizing, .


That process is what the drug family like/similar to Metformin downgrade... slowing the breakdown of protein into glucose. I tried Metformin and watched blood sugars... at 1000 mg dosage I saw really no effect. Yet mostly low carb at that time and fit w decent low body fat... I was more interested in the long term benefits
some extolled on Metformin. Think for the fit it's a non starter... I saw no reason to continue. Aspirin low dose yes.. not Metformin.

The body mechanisms that regulate metabolism et al are simply amazing in complexity. Then the genetic diversity of the population.. most of which is not fit.. pharmaceuticals can only get richer.

WannabeWeenie
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by WannabeWeenie

WinterRider wrote:I tried Metformin and watched blood sugars... at 1000 mg dosage I saw really no effect. Yet mostly low carb at that time and fit w decent low body fat... I was more interested in the long term benefits
some extolled on Metformin. Think for the fit it's a non starter... I saw no reason to continue. Aspirin low dose yes.. not Metformin.


Are you a Type II diabetic? I am one and found that fueling/medicating for rides has been rather hit or miss for me. I experimented with skipping the Metformin dose before each ride for a month. Higher average speeds over the same course during that month seemed to indicate a positive effect. However, a higher A1C despite a more intense level of exercise prompted me to get back on Metformin on a regular shedule.

Can you share what your regimen is, please?

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WinterRider
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by WinterRider

WannabeWeenie wrote:
WinterRider wrote:I tried Metformin and watched blood sugars... at 1000 mg dosage I saw really no effect. Yet mostly low carb at that time and fit w decent low body fat... I was more interested in the long term benefits
some extolled on Metformin. Think for the fit it's a non starter... I saw no reason to continue. Aspirin low dose yes.. not Metformin.


Are you a Type II diabetic? I am one and found that fueling/medicating for rides has been rather hit or miss for me. I experimented with skipping the Metformin dose before each ride for a month. Higher average speeds over the same course during that month seemed to indicate a positive effect. However, a higher A1C despite a more intense level of exercise prompted me to get back on Metformin on a regular shedule.

Can you share what your regimen is, please?


Not type ll... result of reading too many research papers extolling the long term use of Metformin. In the end the basis of those results are tied to blood glucose control.. which I do not need. If Metformin is a positive route for users not requiring BG control no one really knows. So being a chem I decided to discontinue it's use.

I basically eat on the low carb end... low glycemic index range.. when I am going 'right'. Some "cheetin" going on of late.. but not in a big way. And more protein than the general population.. around 1.2 gr/kg per day or higher. Eating less.. slower digesting foods .. huge green salad last meal.. works for me.

WannabeWeenie
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by WannabeWeenie

WinterRider, thanks for sharing. Can you point me in the direction of those research papers, please?

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WinterRider
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by WinterRider

https://www.ncbi.nlm.nih.gov/pubmed/

Slew of articles on Metformin. My bookmarked files for it seems to be AWOL.

waltthizzney
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by waltthizzney

It is common knowledge in the medical community that low carb "keto" diets only make diabetes worse.

Go watch this video

https://www.youtube.com/watch?v=es4PFR5GZTY

rd
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by rd

I was going to post a similar reply to what's above. Low-carb diets are necessarily higher in protein and fat which causes ectopic fat accumulation and through a variety of mechanisms impairs insulin sensitivity resulting in higher blood glucose.

Another good summary from Greger here: https://nutritionfacts.org/video/lipotoxicity-how-saturated-fat-raises-blood-sugar/

Click on the "Sources Cited" tab to get started on the literature.

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WinterRider
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by WinterRider

"low carb "keto" diets"

NOT... everyone eating reduced carbs is KETO. Takes very low carb intake to induce keto... talk about seeing things only one way........... :noidea:

And .. what the FEW ever consider is genetic diversity. Not everyone responds to a given diet in the same manner. This goes doubly for the 'educated' types... especially the 'U-boob' authors.

rd
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by rd

On the off-chance this^ was directed at me, I wasn't conflating low-carb and ketogenic diets. The peer-reviewed literature I linked isn't focused on ketosis, rather saturated fat's contribution to blood glucose, insulin response, oxidation and mitochondrial function.

As an aside: Barnard and Greger are educated, not 'educated'. The former is adjunct associate professor of medicine at the GW University School of Medicine and Health Sciences and the founding president of the Physicians Committee for Responsible Medicine (in additional to being a physician and clinical researcher). The latter does indeed have a YouTube channel; in addition to being a GP specialising in clinical nutrition. I imagine YouTube is a very a useful tool for delivering what is normally quite dense, impenetrable data/concepts in easily searchable and digestible chunks.

Best of luck on your journey towards better health.

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WinterRider
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by WinterRider

rd wrote:On the off-chance this^ was directed at me, I wasn't conflating low-carb and ketogenic diets. The peer-reviewed literature I linked isn't focused on ketosis, rather saturated fat's contribution to blood glucose, insulin response, oxidation and mitochondrial function.

As an aside: Barnard and Greger are educated, not 'educated'. The former is adjunct associate professor of medicine at the GW University School of Medicine and Health Sciences and the founding president of the Physicians Committee for Responsible Medicine (in additional to being a physician and clinical researcher). The latter does indeed have a YouTube channel; in addition to being a GP specialising in clinical nutrition. I imagine YouTube is a very a useful tool for delivering what is normally quite dense, impenetrable data/concepts in easily searchable and digestible chunks.

Best of luck on your journey towards better health.


Not really.. directly. Suffice to say I have a considerable reservoir of skepticism for the medical establishments. We'll leave it at that... :unbelievable:

AJS914
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by AJS914

There was an article in Wired recently about Metformin as an anti-aging drug:

https://www.wired.com/story/this-pill-p ... kel-a-pop/

It sounds like Silicon Valley billionaires are taking it.

by Weenie



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