Ive run MSW on Red AXS equipped bike since new (well about 500kms)
The chain runs 100% silent for about 40-50km and then starts to get louder.
By the time it gets to 250-260k's I can tell its almost time to rewax @ 300kms and depending on what ride Ive got planned next and if my second chain also needs to be waxed (I do them both at the same time) I may re-wax a little early.
I still cant detect any wear after about 10000k's on two chains, but I do note Adam's caution on using a chain checker to detect wear on the AXS chains due to the oversized rollers so will check wear with my digital calipers (by measuring the length of 10 links) as soon as I get around to buying a new battery for them
As far as cleaning the chain goes, I just pour boiling water over the chains to clean before I wax to keep the wax cleaner for as long as possible (yes Im cheap)