Full disclosure - I work for La Fuga - but if you fancy a Tarmac, and are going to be reselling some parts to keep cost reasonable anyway, I thought you might be interested in one of the Tarmac Expert bikes we're selling.http://lafuga.cc/story/bike-sales
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They have been fantastic bikes for us all season... and the only difference between the 10R carbon on these Pro frames versus the 11R carbon S-Works frames is about 75g worth of weight. The overall stiffness and ride quality are near-equal between the two models, it's just that the S-Works wins in stiffness-to-weight.
In terms of ride-quality, there are racier frames out there, but the Specialized is as comfortable a bike as I've ridden, while still being more then enough for any of the riding or racing that I've subjected it to.