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PostPosted: Fri Feb 07, 2014 2:12 pm 
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Location: Geneva, Switzerland
Interesting study shows that antioxidant supplements hampered cellular adaptions in the exercised muscles in endurance training.

Link to abstract


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Posted: Fri Feb 07, 2014 2:12 pm 


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PostPosted: Fri Feb 07, 2014 2:37 pm 
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Keep in mind it did not translate into a performance decrease. Supplementation with vitamin E and C is also likely not very useful for the average athlete eating a complete diet on a daily basis.

A lot of the studies on antioxidant potential mechanisms come up with somewhat limited results and conclusions. Other antioxidants such as polyphenols, particularly flavonoids, could have potential benefits on oxidative stress and play a role in the treatment/prevention of chronic disease such as atherosclerosis, T2DM, and their cardiovasculars consequences.


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PostPosted: Sat Feb 08, 2014 1:02 am 
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Nutritional scientist Stacy Sims says don't take antioxidants or eat things like berries for several hours after training.


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PostPosted: Sat Feb 08, 2014 2:44 am 
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Why after training and not before? Might as well avoid, coffee, tea, cocoa, chocolate, vegetables, fruits, etc, etc, etc.

Piece of shit advice, me say


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PostPosted: Sat Feb 08, 2014 6:10 pm 
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Interesting.

I would just point out that since both groups showed equal improvement, the antioxidants really didn't "hamper" anything.
What the study actually said was :
"Daily vitamin C and E supplementation attenuated increases in markers of mitochondrial biogenesis following endurance training."

So there a a bazillion ways to interpret that. Maybe the antioxidents more successfully protected the mitochondria from damage, so that there was less mitochondrial biogenisis required;
Maybe the "markers" of biogenesis are in a biochemichal pathway that is not as reliable a marker as was previously believed.

Many others possible.
The main point being just that "hampering" is not really a justified conclusion.


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PostPosted: Sun Feb 09, 2014 2:44 pm 
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fuel for the fire

http://www.ncbi.nlm.nih.gov/pubmed/20019626


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PostPosted: Wed Feb 19, 2014 12:23 am 
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Also, in the first study they gave 1000mg of C, and 235mg of E. Those are high doses. I suspect there's nothing to worry about if you take a plain old multivitamin .

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PostPosted: Wed Feb 19, 2014 1:56 am 
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Or what about taking plain old real food and nothing else? ;)


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PostPosted: Fri Feb 21, 2014 1:45 pm 
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Don't know if I believe most of that data...still sounds suspect to me


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PostPosted: Sat Feb 22, 2014 5:12 pm 
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Here is something to marinate on.

http://www.runnersworld.com/nutrition-f ... upplements

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PostPosted: Sat Feb 22, 2014 9:50 pm 
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Oxidative stress and endurance training adaptations sometimes appear to be linked at the molecular level. Oxidative stress is a natural phenomena and intensive exercise induces oxidative stress.


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PostPosted: Tue Mar 04, 2014 2:28 am 
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http://www.ncbi.nlm.nih.gov/m/pubmed/24 ... 20training

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PostPosted: Tue Mar 04, 2014 5:33 am 
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Would anyone like to comment on the size of the error bars and what impact that has on the significance of the measurements?

:thumbup:


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PostPosted: Tue Mar 04, 2014 1:47 pm 
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The abstract for this paper is poor, You can't deduct anything for it. Does anyone have a link to the full paper?

Tapeworm wrote:
http://www.ncbi.nlm.nih.gov/m/pubmed/24576857/?i=8&from=exercise,%20training

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Posted: Tue Mar 04, 2014 1:47 pm 


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PostPosted: Sun Mar 09, 2014 1:59 pm 
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The fun stuff with science is it seems to contradict itself over and over again.

As per Vaughan et al. 2013 review, some antioxidant can induce important intereactions at the molecular level to improve skeletal muscle adaptatons. Polyphenols compound such as epigallocatechin gallate found in tea as been shown to increase circulating catecholamines which are mediator to the expression of key transcription factor activator for mitochondrial biosynthesis.

Additionaly, long chain fatty acids like EPA/DHA found mainly in fish (fish oil) were found to induce molecular activities promoting mitochindrial biosynthesis. A bit out of the antioxidant topic but still good food for thoughts for people considering supplementation as a strategy to improve fitness.


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