You can try : http://titaniumspindles.com/
The "obvious" answer is that the Looks have more stack height, so you effectively lowered your saddle when you switched back. But you said you had a professional fit and tried many adjustments...
The OP stated "frontal knee pain". Anterior knee pain would normally be associated with a saddle that is too low. Speedplays would have effectively raised his saddle. The IT band issues on the other hand can be caused by too much float, saddle too high, too far back, too much foot internal rotation.
SW, I would second your comments.
I'm just thinking out loud and human physiology isn't my area of expertise (plant biotechnology and genetics is): I wonder if the excessive float or float that allows lateral movement too easily causes the stability muscles to have to work more. For example, if I walk on soft sand or ice (think: speedplay float system), the muscles around my knees are having to work harder to keep my foot in the correct orientation relative to the direction of travel. Contrast this with, for example, walking along a dirt road when a small amount of movement (twist) is allowed as the foot strikes the ground and this is good as it helps the foot orient itself more correctly (think: look red cleat with friction) than what it might if it were on concrete and in joggers (effectively zero twist at the feet) (think: look black cleat). In the case of the walking on ice situation, when done for excessive periods of time, muscles would tighten to help stabilise the joint OR your body might start to walk with it's movement extended towards it's upper limits in one direction (for example, on the bike, this may mean pedaling with the heels outwards). Pedaling with the heels outwards would cause enhanced use of the outer quad (vastus lateralis) and probably hip/glute tensors and decreased use of the inner quad. This could affect tracking of the patella over the knee joint as it extends (front of the knee pain) or may be associated with over-tightening of the ITB (which is associated with outer knee pain).
Now, it's not hard to imagine that rocking of the feet (caused by having an unstable platform) could also lead to similar problems. I've often mused of Specialized claims of increased efficiency with their BG shoes by sloping the foot outwards. If tight ITBs are such a big problem with cyclists, why would you want to have the ITB even tighter by rolling the foot outwards?
If there are any physios/doctors/ex physiologists out there that could contribute there thoughts for the greater good, that would be excellent!