I recently purchased a new set of custom wheels so have been riding them and my bike makes absolutely no sounds. I put my Mavic Ksyrium SL's back on for a ride and when ever I am out of the saddle pedaling with effort the front wheel will make a pretty loud ticking noise. I will not be using the Mavics on a regular basis they have become my spare wheels but I would like to find out what's making the noise. I am using the same force on the skewers maybe even less on the new wheels. (Chris King R45 hubs) Any Thoughts?

I had a problem like that with the Ksyriums - front and rear. I tried oiling the nipples to no avail. Though they settled after a while - maybe you just need to be more thorough with the oiling, like drench them in oil to near excess?

The worst was the rear where the spokes are crossed, oil did not work but greasing the intersection worked like magic. Front user to tick when out of the saddle mainly.

Make sure its not the valve clicking around in the valve hole. Have you got a threaded valve with the retaining collar tightened down. I put a small 'o' ring on first to stop it coming loose.

It could be a tiny crack in the rim ,you will only get the ticking sound when you are riding . Is the ticking louder when you put more of your body weight on the wheel ? If so you have a small crack.

Loose hub bearings can also cause this or the lockring isn't tight enough

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N+1 It Never Stops

try a bit of grease on either side of your dropouts

+1, and check the quick releases.

We raced with Ksyrium SL a few years ago when it was our team sponsor...there were a few problems like you have and it was because the loose hub bearings..

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Berk PROTO-TYPE Composites - Handmade In Slovenia
Berk Composites

Make sure you have enough spoke tension in the wheel. Ksyriums will creak if the spokes are allowed to flex to much under load.

+1. Mine creaked like yours when out of the saddle too. Oiling the nipples and at the hub did the trick. The ticking doesn't go immediately, as mentioned, but usually solved the problem.

Looks like several good tips here, hope one works.

I had a similar problem with my shimano 7900 c24's, it was because the rear QR wasn't sitting properly and wasn't tight enough. Loosen your rear QR, smack the seat, then do the QR up nice and tight.

It might actually be a functional problem judging by the other responses here, but that's all mine was.

Try a few drop of oil at the spoke insertion points on the hub and nipples... other culprit may be the valve stem banging against the rim... pop your tube out and wrap a single layer of electrical tape around it...